Simvastatin is an HMG CoA reductase inhibitor. Simvastatin blocks the production of cholesterol (a type of fat) in the body.
Simvastatin is used to reduce the total amounts of cholesterol, LDL (bad) cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood. Simvastatin (Zocor) is also used to increase the level of HDL (good) cholesterol in your blood. These actions may reduce the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
Simvastatin may also be used for purposes other than those listed in this medication guide.
What should I discuss with my doctor before taking simvastatin?
Do not take simvastatin without first talking to your doctor if you have liver disease.
Before taking simvastatin, tell your doctor if you
have kidney disease,
drink alcoholic beverages,
have a chronic muscular disease, or
have a blood disorder.
You may not be able to take simvastatin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Simvastatin is in the FDA pregnancy category X. This means that simvastatin is known to cause birth defects if it is taken during pregnancy. Do not take simvastatin if you are pregnant or could become pregnant during treatment.
It is not known whether simvastatin passes into breast milk. Do not take simvastatin without first talking to your doctor if you are breast-feeding a baby.
How should I take simvastatin?
Take simvastatin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
For the greatest effect, simvastatin is usually taken at bedtime or with an evening meal. Follow your doctor's instructions.
Your doctor may want to monitor your liver function with blood tests before starting treatment with simvastatin and every six months after both the start of your treatment and any increase in dose. Depending on the results of these tests, your doctor can determine how much monitoring you will require.
Grapefruit and grapefruit juice may interact with simvastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Eat a low-fat, low-cholesterol diet. To realize beneficial effects from simvastatin, avoid fatty, high-cholesterol foods.
It is important to take simvastatin regularly to get the most benefit.
Do not stop taking simvastatin without first talking to your doctor. Simvastatin may need to be taken on a long-term basis for the treatment of high cholesterol.
Your doctor may want you to have blood tests or other medical evaluations during treatment with simvastatin to monitor progress and side effects.
Store simvastatin at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
What happens if I overdose?
Seek emergency medical attention if an overdose is suspected.
Symptoms of a simvastatin overdose include nausea, diarrhea, stomach distress, and indigestion.
What should I avoid while taking simvastatin?
Grapefruit and grapefruit juice may interact with simvastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Alcohol and simvastatin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.
What are the possible side effects of simvastatin?
Rare cases of muscle problems and liver problems have been associated with the use of simvastatin and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems.
If you experience any of the following serious side effects, stop taking simvastatin and seek emergency medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
decreased urine or rust-colored urine; or
blurred vision.
Other, less serious side effects may be more likely to occur. Continue to take simvastatin and talk to your doctor if you experience
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What drug(s) may interact with simvastatin?
Do not take Simvastatin with any of the following:
amprenavir
atazanavir
clarithromycin
delavirdine
erythromycin
grapefruit juice
indinavir
itraconazole
ketoconazole
lopinavir; ritonavir
mibefradil
nefazodone
nelfinavir
ritonavir
saquinavir
went yeast
Simvastatin may also interact with the following medications:
medicines to lower cholesterol or triglycerides (examples: fenofibrate, gemfibrozil, niacin)
medicine used to stop early pregnancy (mifepristone, RU-486)
nicardipine
oxcarbazepine
phenytoin
rifampin, rifabutin, or rifapentine
St. John's Wort
telithromycin
troleandomycin
verapamil
voriconazole
warfarin
What is the shelf life of the pills?
The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.
What You Need to Know About Caralluma Fimbriata
Caralluma fimbriata is a succulent plant, in the cactus family, that has been used as a natural appetite suppressant in India for centuries. It's a new arrival in the family of cactii and succulent plants that are becoming increasingly popular for th...
alli Weight Loss Pill
Time is ticking on the miracle diets, the untested, the untrue. Now you can look at weight loss differently. alli™ is the only FDA approved, over-the-counter weight loss product. But it's more than just a pill. It's an innovative weight loss program....
The My Alli Weight Loss Plan
They My Alli Weight Loss Plan was created by nationally recognized nutrition and weight management experts who understand the challenges of losing weight. Read more about one of those experts who has joined the alli team, Dr. Gary Foster. Gary Foster...
Erectile dysfunction (ED) affects the lives of many middle-aged men and their partners. The term erectile dysfunction covers a range of disorders, but usually refers to the inability to obtain an adequate erection for satisfactory sexual activity.
Although erectile dysfunction, formerly called impotence, is more common in men older than 65, it can occur at any age. An occasional episode of erectile dysfunction happens to most men and is normal. As men age, it's also normal to experience changes in erectile function. Erections may take longer to develop, may not be as rigid or may require more direct stimulation to be achieved. Men may also notice that orgasms are less intense, the volume of ejaculate is reduced and recovery time increases between erections. Erectile dysfunction may also be a sign of a physical or emotional problem that requires treatment.
Erectile dysfunction was once a taboo subject, but more men are seeking help. Doctors are gaining a better understanding of what causes erectile dysfunction and are finding new and better treatments.
This Website discusses all about erectile dysfunction, physiology of the normal erection and the pathophysiology, and treatment of ED.
What is Erectile Dysfunction?
Erectile dysfunction or impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis for satisfactory sexual intercourse regardless of the capability of ejaculation. There are various underlying causes, such as diabetes, many of which are medically reversible.
The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect.
Due to its embarrassing nature and the shame felt by sufferers, the subject was taboo for a long time, and is the subject of many urban legends. Folk remedies have long been advocated, with some being advertised widely since the 1930s. The introduction of perhaps the first pharmacologically effective remedy for impotence, sildenafil (trade name Viagra), in the 1990s caused a wave of public attention, propelled in part by the news-worthiness of stories about it and heavy advertising.
The Latin term impotentia coeundi describes simple inability to insert the penis into the vagina. It is now mostly replaced by more precise terms.
Signs and symptoms:
Erectile dysfunction is characterized by the inability to maintain erection. Normal erections during sleep and in the early morning suggest a psychogenic cause, while loss of these erections may signify underlying disease, often cardiovascular in origin. Other things leading to erectile dysfunction are diabetes mellitus (causing neuropathy) or hypogonadism (decreased testosterone levels due to disease affecting the testicles or the pituitary gland).
Here are some causes of Erectile Dysfunction:
* Arousal: The first step is sexual arousal, which men obtain from the senses of sight, touch, hearing and smell, and from thoughts.
* Nervous system response: The brain communicates the sexual excitation to the body's nervous system, which activates increased blood flow to the penis.
* Blood vessel response:. A relaxing action occurs in the blood vessels that supply the penis, allowing more blood to flow into the shafts that produce the erection.
Physiology of normal erections:
Penile erections involve an integration of complex physiologic processes involving the CNS, peripheral nervous system, and hormonal and vascular systems. Any abnormality involving these systems, whether from medication or disease, has a significant impact on the ability to develop and sustain an erection, ejaculate, and experience orgasm. Tumescence, the vascular filling of the cavernous bodies, relies on neural and hormonal mechanisms operating at various levels of the neural axis. This is unique among visceral functions because it requires central neurological input.
Andersson et al summarized some of the information related to the pathways involved in erectile function. The degree of contraction of corpus cavernosal smooth muscle determines the functional state of the penis. The balance between contraction and relaxation is controlled by central and peripheral factors that involve many transmitters and transmitter systems. At the cellular level, smooth muscle relaxation occurs following the release of acetylcholine from the parasympathetic nerves.
Pathophysiology of erectile dysfunction:
Erectile Dysfunction is essentially a vascular disease. It is often associated with other vascular diseases and conditions such as diabetes, hypertension, and coronary artery disease. Other conditions associated with Erectile Dysfunction include neurologic disorders, endocrinopathies, benign prostatic hyperplasia, and depression. Conditions associated with reduced nerve and endothelium function, such as aging, hypertension, smoking, hypercholesterolemia, and diabetes, alter the balance between contraction and relaxation factors. These conditions cause circulatory and structural changes in penile tissues, resulting in arterial insufficiency and defective smooth muscle relaxation. In some patients, sexual dysfunction may be the presenting symptom of these disorders.
Treatment:
Sildenafil Citrate is the way to treat Erectile Dysfunction. Generic Viagra contains sildenafil citrate and contains same ingredients like branded drug.
viagr vviagra viagraa viagrw vaigrs generic viagra buy generic viagra cheap generic viagra cialis generic viagra generic viagra online cialis generic levitra viagra.
cheapest generic viagra buy generic viagra online cheap generic viagra substitute discount generic viagra generic sales viagra buy cheap generic viagra. generic viagra pill
citrate generic sildenafil viagra canadian generic viagra purchase generic viagra generic viagra india order generic viagra generic lowest price viagra generic online order viagra!
cheap generic viagra online cheapest generic price viagra generic viagra soft tab best price for generic viagra cheapest cialis generic viagra viagra generic brand. sildenafil generic viagra
compare generic viagra prices generic viagra from india buy generic viagra online viagra generic drug generic name for viagra generic viagra sale allchemist generic viagra. cheap delivery generic overnight viagra
generic prescription viagra without generic viagra cialis cheap cheapest generic net viagra generic viagra free shipping generic online pharmacy viagra price for generic viagra generic viagra pay with online check.
generic viagra tab generic viagra overnight delivery generic viagrageneric viagra generic viagra caverta compere generic price viagra generic money order viagra, generic overnight viagra! free generic sample viagra
generic viagra on line generic viagra overnight shipping brand drug generic name viagra caverta cheap cialis generic viagra best generic viagra wholesale generic viagra
50mg generic viagra canada generic viagra generic statistics usage viagra canada from generic viagra generic viagra in canada generic mexico pharmacy viagra generic meltabs viagra generic viagra pay pal generic sample viagra!
generic keyword viagra 3 buy cheap generic viagra generic vega viagra best price generic viagra or cialis generic pharmacy viagra generic supply uk viagra free generic viagra generic viagra mexico. generic order viagra viagra used by woman
fake generic viagra cheap generic overnight viagra generic order viagra viagra viagra woman generic viagra and generic drug lowest cost generic viagra generic viagra side effects cialis com generic minuteviagra viagra order generic viagra pay with a check
book.htm generic guest viagra viagra generic brand of viagra online cheapest viagra generic substitute generic viagra usa generic livitra portal viagra day generic next viagra cheap generic india viagra purchase generic viagra online.
generic viagra prescription caverta veega generic viagra generic viagra blue pill 25mg buy generic viagra where generic information viagra generic viagra link generic say viagra wordpress generic viagra review!
